Releases: NCI-Thesaurus/thesaurus-obo-edition
Releases · NCI-Thesaurus/thesaurus-obo-edition
NCIT Release v2024-05-07
Synonyms added: 18744
| Term | New Synonym | Predicate |
|---|---|---|
| Steroid Resistant Acute Graft Versus Host Disease (NCIT:C168582) | Steroid Refractory Acute Graft Versus Host Disease | oio:hasExactSynonym |
| Steroid Resistant Acute Graft Versus Host Disease (NCIT:C168582) | Steroid Refractory Acute GVHD | oio:hasExactSynonym |
| Steroid Resistant Acute Graft Versus Host Disease (NCIT:C168582) | Steroid Resistant Acute GVHD | oio:hasExactSynonym |
| Neuroendocrine Tumor G1 (NCIT:C203250) | NET G1 | oio:hasExactSynonym |
| Neuroendocrine Tumor G1 (NCIT:C203250) | Neuroendocrine Tumor G1 | oio:hasExactSynonym |
| Neuroendocrine Tumor G1 (NCIT:C203250) | Neuroendocrine Tumor Grade 1 | oio:hasExactSynonym |
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Mappings added: 8685
| Subject | Predicate | Object |
|---|---|---|
| Steroid Resistant Acute Graft Versus Host Disease (NCIT:C168582) | subClassOf (rdfs:subClassOf) | Steroid Refractory Graft Versus Host Disease (NCIT:C147114) |
| Recurrent Anaplastic Astrocytoma (NCIT:C136517) | subClassOf (rdfs:subClassOf) | Recurrent Astrocytic Tumor (NCIT:C203274) |
| Recurrent Anaplastic Astrocytoma (NCIT:C136517) | subClassOf (rdfs:subClassOf) | Recurrent Diffuse Glioma (NCIT:C203285) |
| Neuroendocrine Tumor G1 (NCIT:C203250) | subClassOf (rdfs:subClassOf) | Neuroendocrine Tumor (NCIT:C188218) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) | subClassOf (rdfs:subClassOf) | Unresectable Digestive System Adenocarcinoma (NCIT:C129654) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) | subClassOf (rdfs:subClassOf) | Locally Advanced Digestive System Carcinoma (NCIT:C153358) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) | subClassOf (rdfs:subClassOf) | Locally Advanced Unresectable Carcinoma (NCIT:C155698) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) | subClassOf (rdfs:subClassOf) | Locally Advanced Adenocarcinoma (NCIT:C168978) |
| EE99 R1-VAC (NCIT:C203577) | subClassOf (rdfs:subClassOf) | Treatment Arm for EURO-E.W.I.N.G.99 Combination Chemotherapy with or without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients with Ewing's Sarcoma (NCIT:C203561) |
| Sinonasal Angiosarcoma (NCIT:C173125) | subClassOf (rdfs:subClassOf) | Head and Neck Angiosarcoma (NCIT:C202656) |
| CDISC SDTM Category of Tobacco Products Terminology (NCIT:C204434) | subClassOf (rdfs:subClassOf) | Unused Subset Concept (NCIT:C103175) |
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Classes added: 7906
| Term |
|---|
| Neuroendocrine Tumor G1 (NCIT:C203250) |
| Neuroendocrine Tumor G1 (NCIT:C203250) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) |
| EE99 R1-VAC (NCIT:C203577) |
| EE99 R1-VAC (NCIT:C203577) |
| CDISC SDTM Category of Tobacco Products Terminology (NCIT:C204434) |
| CDISC SDTM Category of Tobacco Products Terminology (NCIT:C204434) |
| Vixicovtogene Oboplasmid (NCIT:C203254) |
| Vixicovtogene Oboplasmid (NCIT:C203254) |
| Head and Neck Teratoma (NCIT:C202980) |
| Head and Neck Teratoma (NCIT:C202980) |
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Text definitions added: 3811
| Term | New Text Definition |
|---|---|
| Neuroendocrine Tumor G1 (NCIT:C203250) | A well-differentiated, low-grade epithelial neoplasm with neuroendocrine differentiation. It arises from multiple sites, including the digestive system, lung, and head and neck. |
| Locally Advanced Unresectable Digestive System Adenocarcinoma (NCIT:C202500) | Digestive system adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes and is not amenable to surgical resection. |
| EE99 R1-VAC (NCIT:C203577) | Patients randomized with the following course sequence: 1) Group 1: Vincristine, dactinomycin and cyclophosphamide (VAC) (Dirksen U, et al. J Clin Oncol. 2019 Dec 1;37(34):3192-3202. Le Deley MC, et al. J Clin Oncol. 2014 Aug 10;32(23):2440-8.) |
| CDISC SDTM Category of Tobacco Products Terminology (NCIT:C204434) | Terminology associated with the Category of Tobacco Products codelist of the Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM). |
| Head and Neck Teratoma (NCIT:C202980) | An exceptionally rare mature or immature teratoma that arises from the head and neck region. |
| Subungual Space (NCIT:C204886) | The area underneath a fingernail or toenail. |
| Peribulbar Route of Administration (NCIT:C65041) | Administration of medication under the globe of the eye. |
| Familial Hemophagocytic Lymphohistiocytosis Type 2 (NCIT:C203462) | Familial hemophagocytic lymphohistiocytosis caused by biallelic mutations in the PRF1 gene. |
| Engineered Interferon Alpha-2b Prodrug JZP898 (NCIT:C202905) | An engineered, prodrug form of the human cytokine interferon alpha-2b (IFN-alpha-2b), composed of IFN-alpha-2b linked to a high affinity blockade element via a tumor protease-sensitive linker, and a half-life extension domain, with potential immunomodulatory and antineoplastic activities. Upon administration of engineered IFN-alpha-2b prodrug JZP898, IFN-alpha-2b is bound to the blockade element and pharmacologically inactive. Upon proteolytic cleavage in the tumor microenvironment (TME), active IFN-alpha-2b is released. IFN-alpha-2b binds to specific IFN cell-surface receptors. This activates IFN-mediated signal transduction pathways and induces the transcription and translation of genes with interferon-stimulated response elements (ISREs); the protein products mediate immunomodulating and antiproliferative effects. The selective activation in the TME enhances the IFN-alpha-2b-mediated immune responses against tumor cells while sparing the unwanted effects of systemic, peripheral immune activation. The inclusion of the half-life extension domain prolongs the agent's exposure in the tumor. |
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Text definitions changed: 1201
| Term | Old Text Definition | New Text Definition |
|---|---|---|
| Dexamethasone/Lenolidomide/Panobinostat Regimen (NCIT:C181602) | A chemotherapy regimen consisting of dexamethasone, lenolidomide and panobinostat that can be used for the treatment of relapsed or refractory plasma cell (multiple) myeloma. | A regimen consisting of dexamethasone, lenolidomide and panobinostat that can be used for the treatment of relapsed or refractory plasma cell (multiple) myeloma. |
| Reduced-dose FCR Regimen (NCIT:C181206) | A chemoimmunotherapy regimen consisting of reduced-dose fludarabine, cyclophosphamide and rituximab that can be used for the treatment of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). | A regimen consisting of reduced-dose fludarabine, cyclophosphamide and rituximab that can be used for the treatment of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). |
| Thermography (NCIT:C17194) | A diagnostic technique using a thermograph to record the heat produced by different parts of the bod. It can be used to study blood flow and to detect tumors. | A diagnostic technique using a thermograph to record the heat produced by different parts of the body. It can be used to study blood flow and to detect tumors. |
| OFF Regimen (NCIT:C114101) | A chemotherapy regimen that includes leucovorin, 5-fluorouracil and oxaliplatin, which may be used in the treatment of pancreatic cancer. | A regimen that includes leucovorin, 5-fluorouracil and oxaliplatin that can be used in the treatment of ampullary and pancreatic adenocarcinoma, and esophageal and esophagogastric junction and gastric cancer, and mucinous neoplasms of the ovary. |
| Carboplatin/Cetuximab/Docetaxel Regimen (NCIT:C150690) | A chemoimmunotherapy regimen consisting of carboplatin, docetaxel and cetuximab that can be used for the treatment of head and neck cancer and non-small cell lung cancer (NSCLC). | A regimen consisting of carboplatin, docetaxel and cetuximab that can be used for the treatment of head and neck cancer and non-small cell lung cancer (NSCLC). |
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Synonyms removed: 2460
| Term | Removed Synonym |
|---|---|
| White Oak Pollen IgE Antibody Measurement (NCIT:C147282) | C147282 |
| White Oak Pollen IgE Antibody Measurement (NCIT:C147282) | White Oak Pollen IgE Antibody |
| White Oak Pollen IgE Antibody Measurement (NCIT:C147282) | White Oak Pollen IgE Antibody |
| Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 (NCIT:C136877) | Clinical Stage III Merkel Cell Carcinoma AJCC v8 |
| Cutaneous Merkel Cell Carcinoma by AJCC v7 Stage (NCIT:C136869) | Merkel Cell Carcinoma by AJCC v7 Stage |
| Cutaneous Merkel Cell Carcinoma by AJCC v7 Stage (NCIT:C136869) | Neuroendocrine Carcinoma of the Skin by AJCC v7 Stage |
| German Cockroach IgE Antibody R... |
NCIT Release 2023-10-19
Contributors
balhoff and matentzn
Assets 13
NCIT Release v2022-08-19
What's Changed
Full Changelog: https://github.com/NCI-Thesaurus/thesaurus-obo-edition/commits/v2022-08-19
Contributors
balhoff