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GO:0000055 | ribosomal large subunit export from nucleus | IBA with PTN000529705 , locus:2033661 #5558

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ValWood opened this issue Nov 29, 2024 · 0 comments
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@ValWood
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ValWood commented Nov 29, 2024

  • PTHR ID & PTN node:

GO:0000055 | ribosomal large subunit export from nucleus | IBA with PTN000529705 , locus:2033661

  • Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPCC737.08 and all others

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

Midasin's primary function is in pre-60S Assembly: to remove specific assembly factors from the pre-60S ribosomal subunit.
Proper maturation is a prerequisite for the subsequent recruitment of export factors but midasin doesn't seem to have a direct role in transport.

In fact the TAIR description (i.e annotation source) is

Represents a homolog of the yeast MDN gene, which encodes a non-ribosomal protein involved in the maturation and assembly of the 60S ribosomal subunit. In Arabidopsis, it is essential for female gametogenesis progression.

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