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Issue 29329 #29332

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merged 3 commits into from
Nov 29, 2024
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Issue 29329 #29332

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42febd7
obsoleted term fixes #29329
pgaudet Nov 29, 2024
51bdd6c
obsoleted term for #29330
pgaudet Nov 29, 2024
f54c846
obsoleted term for #29330
pgaudet Nov 29, 2024
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32 changes: 20 additions & 12 deletions src/ontology/go-edit.obo
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Expand Up @@ -78449,9 +78449,9 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
id: GO:0008397
name: sterol 12-alpha-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O." [GOC:mah]
def: "Catalysis of the reaction: a steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-alpha-hydroxysteroid + oxidized [NADPH--hemoprotein reductase]- H2O +H+." [EC:1.14.14.139]
synonym: "cytochrome P450 CYP8B1" NARROW []
xref: EC:1.14.14.139
xref: EC:1.14.14.139 {source="skos:exactMatch"}
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24843" xsd:anyURI
Expand Down Expand Up @@ -160583,11 +160583,12 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
id: GO:0030343
name: vitamin D3 25-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O." [ISBN:0471331309, MetaCyc:RXN-9829]
def: "Catalysis of the reaction: calciol (vitamin D3) + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase]+ + H2O +H2." [RHEA:32903]
synonym: "cholecalciferol 25-hydroxylase activity" EXACT []
xref: EC:1.14.14.24 {source="skos:exactMatch"}
xref: MetaCyc:RXN-9829
xref: RHEA:32903
is_a: GO:0070643 ! vitamin D 25-hydroxylase activity
xref: RHEA:32903 {source="skos:exactMatch"}
is_a: GO:0008395 ! steroid hydroxylase activity
relationship: part_of GO:0036378 ! calcitriol biosynthetic process from calciol

[Term]
Expand Down Expand Up @@ -196840,12 +196841,12 @@ id: GO:0033778
name: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+." [PMID:10051404, PMID:1400444, RHEA:46752]
synonym: "7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity" RELATED [EC:1.14.14.139]
xref: KEGG_REACTION:R04826
xref: MetaCyc:1.14.13.95-RXN
xref: RHEA:46752
is_a: GO:0008397 ! sterol 12-alpha-hydroxylase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24843" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29331" xsd:anyURI

[Term]
id: GO:0033779
Expand All @@ -196859,6 +196860,7 @@ xref: MetaCyc:1.14.13.96-RXN
xref: RHEA:15261
is_a: GO:0008397 ! sterol 12-alpha-hydroxylase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24843" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29331" xsd:anyURI

[Term]
id: GO:0033780
Expand Down Expand Up @@ -372596,14 +372598,17 @@ creation_date: 2009-05-08T02:47:41Z

[Term]
id: GO:0070643
name: vitamin D 25-hydroxylase activity
name: obsolete vitamin D 25-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the hydroxylation of C-25 of any form of vitamin D." [GOC:BHF, GOC:mah]
def: "OBSOLETE. Catalysis of the hydroxylation of C-25 of any form of vitamin D." [GOC:BHF, GOC:mah]
comment: This term was obsoleted because it was an unnecessary grouping term.
synonym: "calciferol 25-hydroxylase activity" NARROW [GOC:mah]
synonym: "cholecalciferol 25-hydroxylase activity" NARROW [GOC:mah]
synonym: "ergocalciferol 25-hydroxylase activity" NARROW [GOC:mah]
synonym: "vitamin D2 25-hydroxylase activity" NARROW [GOC:mah]
is_a: GO:0008395 ! steroid hydroxylase activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29330" xsd:anyURI
is_obsolete: true
consider: GO:0030343
created_by: mah
creation_date: 2009-05-08T03:42:29Z

Expand Down Expand Up @@ -394149,11 +394154,14 @@ creation_date: 2011-01-25T05:19:30Z

[Term]
id: GO:0072555
name: 17-beta-ketosteroid reductase (NADPH) activity
name: obsolete 17-beta-ketosteroid reductase (NADPH) activity
namespace: molecular_function
def: "Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+." [GOC:kad, PMID:17074428]
def: "OBSOLETE. Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+." [GOC:kad, PMID:17074428]
comment: This term was obsoleted because it was an unnecessary grouoing term.
synonym: "7beta-ketosteroid reductase activity" EXACT [GOC:kad]
is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29329" xsd:anyURI
is_obsolete: true
consider: GO:0072582
created_by: mah
creation_date: 2011-01-27T11:36:14Z

Expand Down
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