From e130564ee52894cd0aedbc4f787dcadf10af4144 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Mon, 9 Dec 2024 10:57:51 -0800 Subject: [PATCH 01/13] removed unused GraphHandler --- src/globals/graph-handler.ts | 811 ----------------------------------- 1 file changed, 811 deletions(-) delete mode 100644 src/globals/graph-handler.ts diff --git a/src/globals/graph-handler.ts b/src/globals/graph-handler.ts deleted file mode 100644 index c2a2960..0000000 --- a/src/globals/graph-handler.ts +++ /dev/null @@ -1,811 +0,0 @@ -// This is a first attempt at simplifying the data access from bbop graph to gocam graph -// This should be a separate library to ease the reuse throughout both GO and external applications - - -export class GraphHandler { - - EVIDENCE_PARENT = "ECO:0000000"; - BFO_PART_OF = "BFO:0000050"; - GO_BP = "GO:0008150"; - - // Derived from RO, Feb 16, 2021 - // Reference 1: https://www.ebi.ac.uk/ols/ontologies/ro/properties?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FRO_0002418&viewMode=All&siblings=false - // Reference 2: http://purl.obolibrary.org/obo/ro.obo - // Note: should dynamically load RO OBO/OWL to get those relations - RO_CAUSAL = { - "RO:0002418": "causally upstream of or within", - "RO:0002411": "causally upstream of", - "RO:0004046": "causally upstream of or within, negative effect", - "RO:0004047": "causally upstream of or within, positive effect", - "RO:0002012": "occurent part of", - "RO:0002010": "regulates in other organism", - "RO:0002305": "causally upstream of, negative effect", - "RO:0002304": "causally upstream of, positive effect", - "RO:0002412": "immediately causally upstream of", - "RO:0002211": "regulates", - "RO:0002414": "transitively provides input for", - "RO:0002212": "negatively regulates", - "RO:0002630": "directly negatively regulates", - "RO:0002408": "directly inhibits", - "RO:0002409": "indirectly inhibits", - "RO:0002213": "positively regulates", - "RO:0002629": "directly positively regulates", - "RO:0002406": "directly activates", - "RO:0002407": "indirectly activates", - "RO:0002413": "directly provides input for", - "RO:0002578": "directly regulates", - } - - - dbxrefs; - goApiUrl = "https://api.geneontology.org/api/search/entity/autocomplete/"; - - relations_enabled_by = ['http://purl.obolibrary.org/obo/RO_0002333', 'RO_0002333', 'RO:0002333']; - relations_collapsible = ["RO:0002333", "BFO:0000066", "RO:0002233", "RO:0002488", "RO:0002234"]; // 2233 : has input ; 2234 : has output - relations_nestable = {}; - - - bbopGraph = undefined; - bbopGraphBackup = undefined; // this is used to restore the graph if needed - - categories = undefined; - - - - constructor(graph) { - this.setBBOPGraph(graph); - } - - - /** - * Set the current BBOP graph - * @param graph BBOP graph of a GO-CAM - */ - setBBOPGraph(graph) { - this.bbopGraph = graph; - this.bbopGraphBackup = graph.clone(); - this.preprocess(graph); - } - - /** - * Return the current BBOP graph (low level data) - */ - getBBOPGraph() { - return this.bbopGraph; - } - - /** - * Used to restore the BBO graph (low level data) to its original value before manipulation - */ - resetBBOPGraph() { - this.setBBOPGraph(this.bbopGraphBackup); - } - - /** - * Set the dbxrefs object - * Used to map CURIE <-> resolvable Web URLs - */ - setDBXrefs(dbxrefs) { - this.dbxrefs = dbxrefs; - } - - /** - * Return the dbxrefs object currently loaded - * Used to map CURIE <-> resolvable Web URLs - */ - getDBXrefs() { - return this.dbxrefs; - } - - /** - * Fold a BBOP graph into a GO-CAM graph - * @param graph BBOP graph - * @param graphFold - * @param nest - */ - preprocess(graph, graphFold = "editor", nest = "no") { - - // Prepare graph - graph.unfold(); - if (graphFold == "evidence") { - graph.fold_evidence(); - } else if (graphFold == "editor") { - graph.fold_go_noctua(this.relations_collapsible) - } - - - // Get a list of all the singletons we start with. - var all_starting_singletons_by_id = {}; - var sings = graph.get_singleton_nodes(); - for (let sing of sings) { - all_starting_singletons_by_id[sing.id()] = true; - } - - - // Remove all of the undesireable rels. - var parent_trap = {}; - var note_sink = {}; // keep the reverse lookup info of parent_trap - if (nest && nest === 'yes') { - // console.log('adding nestable rels'); - this.relations_nestable["BFO:0000050"] = true; // part of - } - - for (let e of graph.all_edges()) { - if (this.relations_nestable.hasOwnProperty(e.predicate_id())) { - if (!parent_trap.hasOwnProperty(e.subject_id())) { - parent_trap[e.subject_id()] = []; - } - parent_trap[e.subject_id()].push(e.object_id()); - // Note the object for later checking. - note_sink[e.object_id()] = true; - } - // if(this.relations_strippable.hasOwnProperty(e.predicate_id())) { - // graph.remove_edge(e.subject_id(), - // e.object_id(), - // e.predicate_id()); - // } - } - - - // If it wasn't a singleton before we started, but is one now, - // remove it. In "nest" mode, only remove ones that are not - // going to be nested. - var eings = graph.get_singleton_nodes(); - for (let eing of eings) { - if (!all_starting_singletons_by_id.hasOwnProperty(eing.id())) { - if (nest && nest === 'yes' && note_sink[eing.id()]) { - // pass - } else { - graph.remove_node(eing.id()); - } - } - }; - - let cat_set = new Set(); - for (let enode of this.bbopGraph.all_nodes()) { - for (let in_type of enode.types()) { - cat_set.add(in_type.category()); - } - } - this.categories = Array.from(cat_set); - } - - - - /** - * Return all GO-CAM activity nodes using the GO-CAM activity object (not the bbop node) - */ - getAllActivities() { - let nodes = this.bbopGraph.all_nodes(); - let activities = nodes.filter(node => node.root_types().some(type => type.class_id() == "GO:0003674")) - let betterActivities = []; - for (let activity of activities) { - betterActivities.push(this.getActivity(activity.id())); - } - return betterActivities; - } - - /** - * Return a GO-CAM activity object - * @param nodeId gocam node id e.g. gomodel:568b0f9600000284/57ec3a7e00000119 - */ - getActivity(nodeId) { - - // If no id provided, no activity returned - if (!nodeId) { console.error("no id provided"); return undefined; } - - // If id is not from gomodel space (hardcoded bad), no activity returned - if (nodeId.substring(0, 8) != "gomodel:") { console.error("wrong id provided"); return undefined; } - - // if not couldn't be retrieved, no activity returned - let node = this.bbopGraph.get_node(nodeId); - if (!node) { console.error("could not get bbop graph node ", nodeId); return undefined; } - - - // nodes connected to this activity - let subgraph = node.subgraph(); - - // console.log("getActivity(", nodeId , "): ", subgraph); - - // this will detect the associated biological context - let standardTypes = node.types(); - let inferredTypes = node.get_unique_inferred_types(); - let geneProducts = [] - let biocontext = {}; - let hook_list = [] - if (subgraph) { - let connectedNodes = subgraph.all_nodes(); - for (let connected of connectedNodes) { - // don't treat if same node - if (node.id() == connected.id()) { continue; } - - let edges = subgraph.get_edges(node.id(), connected.id()); - for (let edge of edges) { - - // we are only interested in edges with enabled_by relation - if (!this.relations_enabled_by.includes(edge.predicate_id())) { continue } - - geneProducts.push({ - id: this.nodeIDs(connected)[0], - label: this.nodeLabels(connected)[0], - evidences: this.nodeEvidences(edge) - }); - } - } - - // Do it both ways--upstream and downstream. - this._folded_stack_gather(node, subgraph, 'standard', hook_list, biocontext); - this._folded_stack_gather(node, subgraph, 'reverse', hook_list, biocontext); - // convert to array - for (let key of Object.keys(biocontext)) { - biocontext[key] = Array.from(biocontext[key]); - } - } - - - // the graph must NOT be processed to remove part of as it was before - let partOf = []; - this.getNestedPartOfs(nodeId, partOf) - - - // var x_node = subgraph.get_node(entity_id); - // if(x_node) { - // var ev_node_anns = x_node.get_annotations_by_key('evidence'); - // // console.log("node evs: ", ev_node_anns); - // } - - let annotations = node.annotations(); - let annotationMap = {}; - for (let ann of annotations) { - let cs = new Set(); - if (ann.key() in annotationMap) { - cs = annotationMap[ann.key()] - } else { - annotationMap[ann.key()] = cs; - } - cs.add(ann.value()); - } - // convert to array - for (let key of Object.keys(annotationMap)) { - annotationMap[key] = Array.from(annotationMap[key]); - } - // console.log("node annotations: ", annotationMap); - - return { - nodeId: nodeId, - ids: standardTypes.map(elt => elt.class_id()), - labels: standardTypes.map(elt => elt.class_label()), - partOf: partOf, - biocontexts: biocontext, - geneProducts: geneProducts, - contributors: "contributor" in annotationMap ? annotationMap["contributor"] : [], - providedBy: "providedBy" in annotationMap ? annotationMap["providedBy"] : [], - date: "date" in annotationMap ? annotationMap["date"][0] : "N/A", - raw: { - node: node, - stdTypes: standardTypes, - infTypes: inferredTypes, - annotations: annotationMap, - } - } - } - - getNestedPartOfs(nodeId, partOfs: any[]) { - let edges = this.bbopGraph.get_edges_by_subject(nodeId); - for (let edge of edges) { - if (edge.predicate_id() == this.BFO_PART_OF) { - let object = this.bbopGraph.get_node(edge.object_id()); - if (object.root_types().some(elt => elt.class_id() == "GO:0008150")) { - - let keys = Object.keys(object._id2type) - for (let key of keys) { - let node = object._id2type[key]; - - // console.log("id2type: ", node); - if (node.class_id() == "GO:0008150") { continue; } - - let outEdges = this.bbopGraph.get_edges_by_subject(object.id()); - - if (outEdges && Array.isArray(outEdges) && outEdges.length === 0) { - partOfs.push({ - id: node.class_id(), - label: node.class_label(), - evidences: this.nodeEvidences(edge) - }) - } - - } - } - - //avoid overflow; low chances - if (partOfs.length < 10) { - this.getNestedPartOfs(object.id(), partOfs) - } - } - } - } - - /** - * This will return a list of activities enriched with additional meta data, such as gene taxon and URLs - * Note: require dbxrefs to be set - * @param activities : array of activities returned for instance by getAllActivities() - */ - async enrichActivities(activities) { - let enriched = []; - for (let activity of activities) { - enriched.push(this.enrichActivity(activity)); - } - return Promise.all(enriched); - } - - processesKey(array) { - let key = array.map(elt => elt.id).join(","); - // if not part of BP, state "Other processes" - if (key == "") { key = "Other processes" } - return key - } - - groupActivitiesByProcess(enrichedActivities) { - let map = new Map(); - for (let enr of enrichedActivities) { - let key = this.processesKey(enr.partOf); - // console.log("activity: ", enr , ": process: ", key); - let acts = []; - if (map.has(key)) { - acts = map.get(key); - } else { - map.set(key, acts); - } - acts.push(enr); - } - - let groupedActivities = []; - map.forEach((val, process) => { - let item = { - id: process.split(","), - url: (process.split(",") != "" && this.dbxrefs) ? - process.split(",").map(elt => { - let db = elt.split(":")[0]; - let id = elt.split(":")[1]; - return this.dbxrefs.getURL(db, undefined, id) - }) : "#", - label: val[0].partOf.map(elt => elt.label) == "" ? ["others processes"] : val[0].partOf.map(elt => elt.label), - activities: val - }; - groupedActivities.push(item); - }) - return groupedActivities; - } - - - /** - * This will return an activity enriched with additional meta data, such as gene taxon and URLs - * Note: require dbxrefs to be set - * @param activity : activity object returned by getActivity() - */ - async enrichActivity(activity) { - - for (let gp of activity.geneProducts) { - let metas = null;//await this.annotate(gp.id); - - // if no meta retrieved, continue - if (!metas) { continue; } - - // add hyperlink to gene - gp.url = metas.url; - - if (metas.taxon) { - let db = metas.taxon.split(":")[0]; - db = "taxon" // temp fix - let id = metas.taxon.split(":")[1]; - gp.taxonId = metas.taxon; - gp.taxonLabel = metas.taxon_label; - gp.taxonURL = this.dbxrefs.getURL(db, undefined, id); - } - } - - activity.urls = [] - for (let goid of activity.ids) { - let db = goid.split(":")[0]; - let id = goid.split(":")[1]; - activity.urls.push(this.dbxrefs.getURL(db, undefined, id)); - } - - return activity; - } - - getCausalActivities(activity, enrichedActivities) { - let connected = {}; - let edges = this.bbopGraph.get_edges_by_subject(activity.nodeId); - for (let edge of edges) { - - // console.log("edge: ", edge); - if (!this.RO_CAUSAL.hasOwnProperty(edge.predicate_id())) { - continue; - } - - let object = this.bbopGraph.get_node(edge.object_id()); - // console.log("object: ", object); - - let keys = Object.keys(object._id2type) - let isActivity = false; - for (let key of keys) { - let node = object._id2type[key]; - - if (node.class_id() == "GO:0003674") { - isActivity = true; - break; - } - - } - - if (isActivity) { - let relid = edge.predicate_id(); - let activities = []; - if (connected.hasOwnProperty(relid)) { - activities = connected[relid]; - } else { - connected[relid] = activities; - } - - activities.push({ - relationId: edge.id(), - relationLabel: edge._predicate_label, - relationURL: this.dbxrefs.getURL(relid.split(":")[0], undefined, relid.split(":")[1]), - activity: this.getActivityById(enrichedActivities, object.id()) - }); - } - } - - return connected; - } - - getActivityById(enrichedActivities, nodeId) { - for (let ea of enrichedActivities) { - if (ea.nodeId == nodeId) { - return ea; - } - } - return null; - } - - - - /** - * Return the URL, taxon and taxon URL for a gene CURIE - */ - async annotate(id) { - if (!id) { - console.error("asked to annotated null id: ", id); - return ""; - } - if (id.includes(":")) { - let category = "category=gene&"; - if (id.includes("GO:")) - category = "" - let url = this.goApiUrl + id + "?" + category + "rows=1"; - return await fetch(url) - .then(async function (data) { return data.json() }) - .then(data => { - let doc = data.docs[0]; - try { - let db = doc.id.split(":")[0]; - let dbid = doc.id.split(":")[1]; - - // Temporary fix for a long standing issue of MGI:MGI: curie - if (doc.id.includes("MGI:") && !doc.id.includes("MGI:MGI:")) { - dbid = "MGI:" + dbid; - } - - doc["url"] = this.dbxrefs.getURL(db, undefined, dbid); - } catch (error) { - console.error("asked to annotate ", id, " but doc ", doc, " does not have an id, can not resolve URL - data is: ", data); - } - return doc - }) - } - } - - - - - - - - - nodeEvidences(edge) { - // should always be there - should always have evidence, but just in case - if (!edge.referenced_subgraphs()) { - console.warn("edge ", edge, " does not have evidence !"); - return []; - } - - let evidences = []; - for (let rfs of edge.referenced_subgraphs()) { - let keys = Object.keys(rfs._nodes); - for (let key of keys) { - let node = rfs._nodes[key]; - - // normally 1 source, 1 with, multiple sources - let evidence = { source: "", url: "", with: "", evidences: [] } - for (let ann of node.annotations()) { - if (ann._properties.key == "source") { - evidence.source = ann._properties.value; - evidence.url = this.dbxrefs.getURL(evidence.source.split(":")[0], undefined, evidence.source.split(":")[1]); - } else if (ann._properties.key == "with") { - evidence.with = ann._properties.value; - } - } - - let evkeys = Object.keys(node._id2type); - for (let evkey of evkeys) { - let ev = node._id2type[evkey]; - if (ev.class_id() != this.EVIDENCE_PARENT) { - evidence.evidences.push({ id: ev.class_id(), label: ev.class_label() }); - } - } - evidences.push(evidence); - } - } - return evidences; - } - - nodeIDs(n) { - var retlist = []; - var bin = {}; - for (let in_type of n.types()) { - var cat = in_type.category(); - if (!bin[cat]) { bin[cat] = []; } - bin[cat].push(in_type); - } - for (let cat_id of this.categories) { - var accumulated_types = bin[cat_id]; - var cell_cache = []; - for (let atype of accumulated_types) { - var tt = atype.class_id(); - cell_cache.push(tt); - } - retlist.push(cell_cache.join("\n")); - }; - return retlist; - } - - nodeLabels(n) { - var retlist = []; - var bin = {}; - for (let in_type of n.types()) { - var cat = in_type.category(); - if (!bin[cat]) { bin[cat] = []; } - bin[cat].push(in_type); - } - for (let cat_id of this.categories) { - var accumulated_types = bin[cat_id]; - var cell_cache = []; - for (let atype of accumulated_types) { - var tt = atype.class_label(); - cell_cache.push(tt); - } - let val = cell_cache.join("\n"); - if (val.includes(" ")) { - let splits = val.split(" "); - splits.pop(); // remove the species - val = splits.join("\n"); - } - retlist.push(val); - }; - return retlist; - } - - nodeIDLabels(n) { - var retlist = []; - var bin = {}; - for (let in_type of n.types()) { - var cat = in_type.category(); - if (!bin[cat]) { bin[cat] = []; } - bin[cat].push(in_type); - } - for (let cat_id of this.categories) { - var accumulated_types = bin[cat_id]; - var ids = []; - var labels = []; - for (let atype of accumulated_types) { - ids.push(atype.class_id()); - labels.push(atype.class_label()); - } - retlist.push({ ids: ids.join("\n"), labels: labels.join("\n") }); - }; - return retlist; - } - - - - // Gather the stack to display, abstractly do go up or down - // the subgraph. - _folded_stack_gather(enode, subgraph, direction, hook_list, biocontext) { - - // First, get the parent/child sub-nodes. - var x_edges = []; - if (direction === 'standard') { - x_edges = subgraph.get_parent_edges(enode.id()); - } else { - x_edges = subgraph.get_child_edges(enode.id()); - } - - // for a specific aspect of the activity - for (let x_edge of x_edges) { - // Edge info. - var rel = x_edge.relation() || 'n/a'; - // TODO var rel_color = aid.color(rel); - // TODO var rel_readable = aid.readable(rel); - var rel_color = "red"; - var rel_readable = "readable_var"; - // If context aid doesn't work, see if it comes with a label. - if (rel_readable === rel && typeof (x_edge.label) === 'function') { - var label_rn = x_edge.label(); - if (label_rn !== rel) { - rel = label_rn; // use label - } - } else { - rel = rel_readable; // use context - } - - // collecting all the evidences for that aspect.... (seriously this business logic should be on the server side to avoid those kind of smelly/spaghetti code) - let gathered_evidences = { "pmid": [], "eco": [], "label": [], "url": [] } - var refsubgraphs = x_edge.referenced_subgraphs(); - for (var refsubgraph of refsubgraphs) { - var refevnodes = refsubgraph.get_nodes() - for (let nodeid of Object.keys(refevnodes)) { - let node = refsubgraph.get_node(nodeid); - let anns = node.annotations(); - for (let ann of anns) { - if (ann._properties["key"] == "source") { - let id = ann._properties["value"]; - gathered_evidences["pmid"].push(id); - if (id && id.includes(":")) { - gathered_evidences["url"].push(this.dbxrefs.getURL(id.split(":")[0], undefined, id.split(":")[1])) - } else { - // could not resolve - gathered_evidences["url"].push("#"); - } - } - } - let types = node.types(); - for (let type of types) { - gathered_evidences["eco"].push(type.class_id()); - gathered_evidences["label"].push(type.class_label()); - } - } - } - - var ev_edge_anns = x_edge.get_annotations_by_key('evidence'); - - // Get node. - var x_ent_id = null; - if (direction === 'standard') { - x_ent_id = x_edge.object_id(); - } else { - x_ent_id = x_edge.subject_id(); - } - - var x_node = subgraph.get_node(x_ent_id); - // console.log("CENTRAL NODE: ", x_ent_id, x_node); - // Try and extract proof of evidence. - if (x_node) { - var ev_node_anns = x_node.get_annotations_by_key('evidence'); - // console.log("utils : node annotation: ", ev_node_anns); - - // Add the edge/node combos to the table. - for (let x_type of x_node.types()) { - // - var elt_id = this.uuid(); - var edge_id = x_edge.id(); - let edge_label = this.glyph(x_edge.relation()).label; - hook_list.push([edge_id, elt_id]); - // console.log("XTYPE: ", x_type); - let relid = x_edge.relation(); - - let cs = new Set(); - if (relid in biocontext) { - cs = biocontext[relid]; - } else { - biocontext[relid] = cs; - } - - cs.add({ - relationId: edge_id, - relationLabel: edge_label, - relationURL: this.dbxrefs.getURL(relid.split(":")[0], undefined, relid.split(":")[1]), - evidences: gathered_evidences, - nodeId: elt_id, - termId: x_type.class_id(), - termLabel: x_type.class_label(), - termURL: this.dbxrefs.getURL(x_type.class_id().split(":")[0], undefined, x_type.class_id().split(":")[1]), - }); - - // In this case (which should be the only possible - // case), we'll capture the ID and pair it with an - // ID. - // _add_table_row(x_type, rel_color, rel + '(', - // ')E'); - - } - } - - } - } - - - /** - * From https://github.com/berkeleybop/bbop-core/blob/master/lib/core.js - * RFC 4122 v4 compliant UUID generator. - * From: http://stackoverflow.com/questions/105034/how-to-create-a-guid-uuid-in-javascript/2117523#2117523 - * - * @returns {string} string - */ - uuid() { - - // Replace x (and y) in string. - function replacer(c) { - var r = Math.random() * 16 | 0, v = c == 'x' ? r : (r & 0x3 | 0x8); - return v.toString(16); - } - var target_str = 'xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx'; - return target_str.replace(/[xy]/g, replacer); - } - - glyph(relation) { - switch (relation) { - case "BFO:0000050": - return { lineStyle: "solid", glyph: null, label: "part of", color: '#add8e6' }; - case "BFO:0000051": - return { lineStyle: "solid", glyph: null, label: "has part", color: '#6495ED' }; - case "BFO:0000066": - return { lineStyle: "solid", glyph: null, label: "occurs in", color: '#66CDAA' }; - case "RO:0002211": - return { lineStyle: "dashed", glyph: null, label: "regulates", color: '#2F4F4F' }; - case "RO:0002212": - return { lineStyle: "dashed", glyph: "tee", label: "negatively regulates", color: '#FF0000' }; - case "RO:0002630": - return { lineStyle: "solid", glyph: "tee", label: "directly negatively regulates", color: '#FF0000' }; - case "RO:0002213": - return { lineStyle: "dashed", glyph: "triangle", label: "positively regulates", color: '#008000' }; - case "RO:0002629": - return { lineStyle: "solid", glyph: "triangle", label: "directly positively regulates", color: '#008000' }; - case "RO:0002233": - return { lineStyle: "solid", glyph: null, label: "has input", color: '#6495ED' }; - case "RO:0002234": - return { lineStyle: "solid", glyph: null, label: "has output", color: '#ED6495' }; - case "RO:0002331": - return { lineStyle: "solid", glyph: null, label: "involved in", color: '#E9967A' }; - case "RO:0002333": - return { lineStyle: "solid", glyph: null, label: "enabled by", color: '#B8860B' }; - case "RO:0002411": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of", color: '#483D8B' }; - case "RO:0002418": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of or within", color: '#483D8B' }; - - case "RO:0002408": - return { lineStyle: "solid", glyph: "tee", label: "directly inhibits", color: '#FF0000' }; - case "RO:0002406": - return { lineStyle: "solid", glyph: "triangle", label: "directly activates", color: '#008000' }; - - case "RO:0002305": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of, negative effect", color: '#FF0000' }; - case "RO:0004046": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of or within, negative effect", color: '#FF0000' }; - - case "RO:0002304": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of, positive effect", color: '#008000' }; - case "RO:0004047": - return { lineStyle: "dashed", glyph: null, label: "causally upstream of or within, positive effect", color: '#008000' }; - - case "annotation": - return { lineStyle: "solid", glyph: "diamond", label: "annotation", color: '#483D8B' }; - case "instance_of": - return { lineStyle: "solid", glyph: null, label: "activity", color: '#FFFAFA' }; - } - console.warn("No glyph found for relation '" + relation + "'"); - return { glyph: null, label: relation, color: "black" }; - } - -} From 832ce7913f66b4b2b64c96202a452ae09e49767f Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Mon, 9 Dec 2024 21:22:26 -0800 Subject: [PATCH 02/13] impreoved the legend to use svg. Relation data type check --- src/components/gocam-legend/gocam-legend.scss | 23 +++ src/components/gocam-legend/gocam-legend.tsx | 103 +++++----- src/components/gocam-viz/gocam-viz.tsx | 16 +- src/globals/constants.ts | 37 ---- src/globals/legend.ts | 21 ++ src/globals/relations.ts | 191 ++++++++++++++++++ src/globals/utils.ts | 172 ---------------- src/styled.html | 3 +- 8 files changed, 305 insertions(+), 261 deletions(-) create mode 100644 src/globals/legend.ts create mode 100644 src/globals/relations.ts diff --git a/src/components/gocam-legend/gocam-legend.scss b/src/components/gocam-legend/gocam-legend.scss index 24cbae0..9ad89c8 100644 --- a/src/components/gocam-legend/gocam-legend.scss +++ b/src/components/gocam-legend/gocam-legend.scss @@ -58,3 +58,26 @@ img { display: inline-block; margin-left: 0.5em; } + +.columns { + display: flex; + gap: 20px; + + .column { + flex: 1; + display: flex; + flex-direction: column; + gap: 10px; + } +} + +.item { + display: flex; + align-items: center; + gap: 5px; + height: 30px; + + svg { + flex-shrink: 0; + } +} diff --git a/src/components/gocam-legend/gocam-legend.tsx b/src/components/gocam-legend/gocam-legend.tsx index e82459e..dcc9a8d 100644 --- a/src/components/gocam-legend/gocam-legend.tsx +++ b/src/components/gocam-legend/gocam-legend.tsx @@ -1,38 +1,9 @@ import { Component, Host, h } from '@stencil/core'; -import { legend } from '../../globals/constants'; +import { RELATION_MAP, STYLES } from '../../globals/relations'; +import { LEGEND_COLUMNS } from '../../globals/legend'; -import direct_regulation from './assets/relation/direct_regulation.png'; -import indirect_regulation from './assets/relation/indirect_regulation.png'; -import positive_regulation from './assets/relation/positive_regulation.png'; -import negative_regulation from './assets/relation/negative_regulation.png'; -import provides_input_for from './assets/relation/provides_input_for.png'; -import neutral from './assets/relation/neutral.png'; -import input_of from './assets/relation/input_of.png'; -import has_output from './assets/relation/has_output.png'; -// Stencil's Assets feature[1] makes client applications jump through a lot of hoops[2] in order -// to get the assets served from the right location if they choose to the NPM package instead of -// a + + + + + wc-gocam-viz -- styled + + + + + + +
+ + +
+ + + + + + + \ No newline at end of file diff --git a/src/globals/legend.ts b/src/globals/legend.ts index b84126a..a6c9685 100644 --- a/src/globals/legend.ts +++ b/src/globals/legend.ts @@ -1,21 +1,21 @@ import { Relations } from "./relations"; export const LEGEND_COLUMNS = { - regulation: [ - Relations.DIRECTLY_POSITIVELY_REGULATES, // RO:0002629 - Relations.DIRECTLY_NEGATIVELY_REGULATES, // RO:0002630 - Relations.INDIRECTLY_POSITIVELY_REGULATES, // RO:0002409 - Relations.INDIRECTLY_NEGATIVELY_REGULATES // RO:0002407 - ], - input: [ - Relations.PROVIDES_INPUT_FOR, // RO:0002413 - Relations.REMOVES_INPUT_FOR, // RO:0012010 - Relations.HAS_INPUT, // RO:0002233 - Relations.HAS_OUTPUT // RO:0002234 - ], - upstream: [ - Relations.CONSTITUTIVELY_UPSTREAM_OF, // RO:0012009 - Relations.CAUSALLY_UPSTREAM_OF_POSITIVE_EFFECT, // RO:0002304 - Relations.CAUSALLY_UPSTREAM_OF_NEGATIVE_EFFECT // RO:0002305 - ] -}; \ No newline at end of file + regulation: { + [Relations.DIRECTLY_POSITIVELY_REGULATES]: 'direct positive regulation/activation', + [Relations.DIRECTLY_NEGATIVELY_REGULATES]: 'direct negative regulation/inhibition', + [Relations.INDIRECTLY_POSITIVELY_REGULATES]: 'indirect positive regulation', + [Relations.INDIRECTLY_NEGATIVELY_REGULATES]: 'indirect negative regulation' + }, + input: { + [Relations.PROVIDES_INPUT_FOR]: 'provides input for', + [Relations.REMOVES_INPUT_FOR]: 'removes input for', + [Relations.HAS_INPUT]: 'input of', + [Relations.HAS_OUTPUT]: 'has output' + }, + upstream: { + [Relations.CONSTITUTIVELY_UPSTREAM_OF]: 'constitutively upstream', + [Relations.CAUSALLY_UPSTREAM_OF_POSITIVE_EFFECT]: 'upstream positive effect', + [Relations.CAUSALLY_UPSTREAM_OF_NEGATIVE_EFFECT]: 'upstream negative effect' + } +}; diff --git a/src/styled.html b/src/styled.html index 29f95d6..ea45c99 100644 --- a/src/styled.html +++ b/src/styled.html @@ -56,8 +56,7 @@
- +
From 9d5bbf49068226b881b5f07cc8e917c499369989 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Tue, 10 Dec 2024 12:34:46 -0800 Subject: [PATCH 04/13] removed the legend assets not used --- src/components/gocam-legend/assets/legend.png | Bin 66420 -> 0 bytes src/components/gocam-legend/assets/legendv2.png | Bin 62745 -> 0 bytes .../assets/relation/direct_regulation.png | Bin 191 -> 0 bytes .../gocam-legend/assets/relation/has_output.png | Bin 477 -> 0 bytes .../assets/relation/indirect_regulation.png | Bin 200 -> 0 bytes .../gocam-legend/assets/relation/input_of.png | Bin 470 -> 0 bytes .../assets/relation/negative_regulation.png | Bin 447 -> 0 bytes .../gocam-legend/assets/relation/neutral.png | Bin 468 -> 0 bytes .../assets/relation/positive_regulation.png | Bin 851 -> 0 bytes .../assets/relation/provides_input_for.png | Bin 1918 -> 0 bytes 10 files changed, 0 insertions(+), 0 deletions(-) delete mode 100644 src/components/gocam-legend/assets/legend.png delete mode 100644 src/components/gocam-legend/assets/legendv2.png delete mode 100644 src/components/gocam-legend/assets/relation/direct_regulation.png delete mode 100644 src/components/gocam-legend/assets/relation/has_output.png delete mode 100644 src/components/gocam-legend/assets/relation/indirect_regulation.png delete mode 100644 src/components/gocam-legend/assets/relation/input_of.png delete mode 100644 src/components/gocam-legend/assets/relation/negative_regulation.png delete mode 100644 src/components/gocam-legend/assets/relation/neutral.png delete mode 100644 src/components/gocam-legend/assets/relation/positive_regulation.png delete mode 100644 src/components/gocam-legend/assets/relation/provides_input_for.png diff --git a/src/components/gocam-legend/assets/legend.png b/src/components/gocam-legend/assets/legend.png deleted file mode 100644 index bce52db1e6e2609ca0c290ad7eb0343ea8c1c0bf..0000000000000000000000000000000000000000 GIT binary patch literal 0 HcmV?d00001 literal 66420 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-0800 Subject: [PATCH 05/13] remove accidental debug.html --- .gitignore | 3 ++ .prettierrc.json | 4 +- src/debug.html | 96 ------------------------------------------------ 3 files changed, 4 insertions(+), 99 deletions(-) delete mode 100644 src/debug.html diff --git a/.gitignore b/.gitignore index c3ea58a..bb21bdd 100644 --- a/.gitignore +++ b/.gitignore @@ -24,3 +24,6 @@ $RECYCLE.BIN/ Thumbs.db UserInterfaceState.xcuserstate .env + + +debug.html \ No newline at end of file diff --git a/.prettierrc.json b/.prettierrc.json index 2f5fc2e..e9ffda5 100644 --- a/.prettierrc.json +++ b/.prettierrc.json @@ -9,7 +9,5 @@ "singleQuote": true, "tabWidth": 2, "trailingComma": "all", - "useTabs": false, - "singleAttributePerLine": true, - "bracketSameLine": false + "useTabs": false } \ No newline at end of file diff --git a/src/debug.html b/src/debug.html deleted file mode 100644 index 29f95d6..0000000 --- a/src/debug.html +++ /dev/null @@ -1,96 +0,0 @@ - - - - - - - - - - - wc-gocam-viz -- styled - - - - - - -
- - -
- - - - - - - \ No newline at end of file From fff90fefc9e1e955418d3eb5e35486cc92c93a42 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Tue, 10 Dec 2024 12:56:48 -0800 Subject: [PATCH 06/13] ran build locally to regenerate the readme files --- src/components/gocam-legend/readme.md | 8 -------- src/components/gocam-viz/readme.md | 4 ++-- 2 files changed, 2 insertions(+), 10 deletions(-) diff --git a/src/components/gocam-legend/readme.md b/src/components/gocam-legend/readme.md index c280422..9bdd73c 100644 --- a/src/components/gocam-legend/readme.md +++ b/src/components/gocam-legend/readme.md @@ -5,14 +5,6 @@ -## Shadow Parts - -| Part | Description | -| ----------- | ----------------------- | -| `"header"` | The header | -| `"section"` | Group of legend entries | - - ## CSS Custom Properties | Name | Description | diff --git a/src/components/gocam-viz/readme.md b/src/components/gocam-viz/readme.md index ba6532b..92544a0 100644 --- a/src/components/gocam-viz/readme.md +++ b/src/components/gocam-viz/readme.md @@ -153,15 +153,15 @@ Type: `Promise` ### Depends on - [go-loading-spinner](../loading-spinner) -- [wc-gocam-legend](../gocam-legend) - [wc-genes-panel](../genes-panel) +- [wc-gocam-legend](../gocam-legend) ### Graph ```mermaid graph TD; wc-gocam-viz --> go-loading-spinner - wc-gocam-viz --> wc-gocam-legend wc-gocam-viz --> wc-genes-panel + wc-gocam-viz --> wc-gocam-legend style wc-gocam-viz fill:#f9f,stroke:#333,stroke-width:4px ``` From 64c525fb58930b2cc62a8b2f84f1233e303cafbd Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Wed, 11 Dec 2024 15:45:50 -0800 Subject: [PATCH 07/13] fixed the styling bugs --- src/components/gocam-legend/gocam-legend.scss | 5 +- src/components/gocam-legend/gocam-legend.tsx | 10 ++- src/components/gocam-legend/readme.md | 9 +++ src/components/gocam-viz/gocam-viz.scss | 20 ++---- src/components/gocam-viz/gocam-viz.tsx | 67 +++++++++---------- src/components/gocam-viz/readme.md | 3 +- 6 files changed, 60 insertions(+), 54 deletions(-) diff --git a/src/components/gocam-legend/gocam-legend.scss b/src/components/gocam-legend/gocam-legend.scss index c9db2fd..bafcb58 100644 --- a/src/components/gocam-legend/gocam-legend.scss +++ b/src/components/gocam-legend/gocam-legend.scss @@ -37,7 +37,6 @@ align-items: center; margin-bottom: 0.2em; gap: 0.25em; - height: 2em; svg { flex-shrink: 0; @@ -49,11 +48,11 @@ margin-left: 0.2em; } -.columns { +.sections { display: flex; gap: 0.25em; - .column { + .section { flex: 1; display: flex; flex-direction: column; diff --git a/src/components/gocam-legend/gocam-legend.tsx b/src/components/gocam-legend/gocam-legend.tsx index 37af683..810dfd8 100644 --- a/src/components/gocam-legend/gocam-legend.tsx +++ b/src/components/gocam-legend/gocam-legend.tsx @@ -3,7 +3,11 @@ import { RELATION_MAP, STYLES } from '../../globals/relations'; import { LEGEND_COLUMNS } from '../../globals/legend'; - +/** + * @part header - The header + * @part sections - Group of legend entries + * @part section - An individual legend entry + */ @Component({ tag: 'wc-gocam-legend', styleUrl: 'gocam-legend.scss', @@ -40,9 +44,9 @@ export class GocamLegend {
Relation Types
-
+
{Object.entries(LEGEND_COLUMNS).map(([columnName, relations]) => ( -
+
{Object.entries(relations).map(([relationId, label]) => { const config = RELATION_MAP[relationId]; return ( diff --git a/src/components/gocam-legend/readme.md b/src/components/gocam-legend/readme.md index 9bdd73c..354490a 100644 --- a/src/components/gocam-legend/readme.md +++ b/src/components/gocam-legend/readme.md @@ -5,6 +5,15 @@ +## Shadow Parts + +| Part | Description | +| ------------ | -------------------------- | +| `"header"` | The header | +| `"section"` | An individual legend entry | +| `"sections"` | Group of legend entries | + + ## CSS Custom Properties | Name | Description | diff --git a/src/components/gocam-viz/gocam-viz.scss b/src/components/gocam-viz/gocam-viz.scss index ebc3cc8..da235d7 100644 --- a/src/components/gocam-viz/gocam-viz.scss +++ b/src/components/gocam-viz/gocam-viz.scss @@ -96,6 +96,8 @@ --legend-border-width: 0; --legend-border-color: var(--border-color); --legend-padding: 0; + --legend-margin: 1rem 0 0 0; + @include standard-var-declarations(legend-header, $border-color: var(--border-color)); @include standard-var-declarations(process, $border-color: var(--border-color)); @@ -116,7 +118,8 @@ --function-nodes-padding: 0; display: flex; - align-items: flex-start; + align-items: stretch; + flex-direction: column; } .gocam-container { @@ -125,19 +128,9 @@ flex-direction: column; } -.gocam-top-section { +.gocam-graph-and-activities-container { display: flex; - flex: 1; - margin-bottom: 1rem; -} - -.gocam-legend-container { - width: 100%; - - wc-gocam-legend { - height: 100%; - width: 100%; - } + align-items: flex-start; } .panel { @@ -197,6 +190,7 @@ button { } wc-gocam-legend { + margin: var(--legend-margin); --border-width: var(--legend-border-width); --border-color: var(--legend-border-color); --padding: var(--legend-padding); diff --git a/src/components/gocam-viz/gocam-viz.tsx b/src/components/gocam-viz/gocam-viz.tsx index c3a333a..a286a8d 100644 --- a/src/components/gocam-viz/gocam-viz.tsx +++ b/src/components/gocam-viz/gocam-viz.tsx @@ -28,7 +28,8 @@ const GOMODEL_PREFIX = "gomodel:" * @part gene-product - A gene product name in process and activities list * @part function-label - A function term name in process and activities list * @part legend-header - The header of the legend - * @part legend-section - A group of entries in the legend + * @part legend-sections - A group of entries in the legend + * @part legend-section - An individual legend entry */ @Component({ tag: 'wc-gocam-viz', @@ -761,46 +762,44 @@ export class GoCamViz { return ( -
-
-
-
-
{this.cam?.title}
-
- - -
-
-
-
this.graphDiv = el}> - {this.loading && - - } -
+
+
+
+
{this.cam?.title}
+
+ +
-
-
- Processes and Activities -
-
- this.genesPanel = el} - > - +
+
this.graphDiv = el}> + {this.loading && + + }
- {this.showLegend && ( -
- +
+
+ Processes and Activities +
+
+ this.genesPanel = el} + > +
- )} +
+ {this.showLegend && ( +
+ +
+ )} ); } diff --git a/src/components/gocam-viz/readme.md b/src/components/gocam-viz/readme.md index 92544a0..7fcca95 100644 --- a/src/components/gocam-viz/readme.md +++ b/src/components/gocam-viz/readme.md @@ -80,7 +80,8 @@ Type: `Promise` | `"gocam-panel"` | The panel containing the GO-CAM graph and legend | | `"gocam-title"` | The GO-CAM title | | `"legend-header"` | The header of the legend | -| `"legend-section"` | A group of entries in the legend | +| `"legend-section"` | An individual legend entry | +| `"legend-sections"` | A group of entries in the legend | | `"process"` | A process group in the process and activities list | From d3be18c732b185b4bdff718825b3aa812c6a5183 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Wed, 11 Dec 2024 15:52:48 -0800 Subject: [PATCH 08/13] Removed the custon-tee styling attempt, since weare now using square instead --- src/components/gocam-viz/gocam-viz.tsx | 14 -------------- 1 file changed, 14 deletions(-) diff --git a/src/components/gocam-viz/gocam-viz.tsx b/src/components/gocam-viz/gocam-viz.tsx index a286a8d..b88ff76 100644 --- a/src/components/gocam-viz/gocam-viz.tsx +++ b/src/components/gocam-viz/gocam-viz.tsx @@ -478,20 +478,6 @@ export class GoCamViz { { selector: 'edge', style: this.defaultEdgeStyle - }, - { - selector: 'edge', - style: { - ...this.defaultEdgeStyle, - 'arrow-shape': function (edge) { - return { - width: 3, - height: 3, - name: 'custom-tee-circle', - path: 'M 0,0 m -1,-1 l 2,0 l 0,2 l -2,0 z M 2,0 a 1,1 0 1,0 2,0 a 1,1 0 1,0 -2,0' - }; - } - } } ], From 3aebcb04a17e6b83ce44d4877fd38ee43cadd5f8 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Wed, 11 Dec 2024 17:47:58 -0800 Subject: [PATCH 09/13] fixed a bug of small molecule not diplaying, now using rootNode --- src/components/genes-panel/genes-panel.tsx | 10 +++++----- src/globals/@noctua.form/services/graph.service.ts | 2 +- 2 files changed, 6 insertions(+), 6 deletions(-) diff --git a/src/components/genes-panel/genes-panel.tsx b/src/components/genes-panel/genes-panel.tsx index 38d4a89..d1f7dd1 100644 --- a/src/components/genes-panel/genes-panel.tsx +++ b/src/components/genes-panel/genes-panel.tsx @@ -169,7 +169,7 @@ export class GenesPanel { renderActivity(activity: Activity) { const nodes = activity.nodes.filter((node: ActivityNode) => ( - node.type !== ActivityNodeType.GoMolecularFunction) + node.predicate?.edge?.id !== '' && node.predicate?.edge?.id !== noctuaFormConfig.edge.enabledBy.id) ); return ( @@ -177,14 +177,14 @@ export class GenesPanel {
{ activity.gpNode && - {activity.gpNode?.term.label} + {activity.gpNode?.term.label} }
- {activity.mfNode && + {activity.rootNode &&
- - {activity.mfNode?.term.label} + + {activity.rootNode?.term.label}
diff --git a/src/globals/@noctua.form/services/graph.service.ts b/src/globals/@noctua.form/services/graph.service.ts index aa67ce4..b8a5201 100644 --- a/src/globals/@noctua.form/services/graph.service.ts +++ b/src/globals/@noctua.form/services/graph.service.ts @@ -102,7 +102,7 @@ export class NoctuaGraphService { } - loadCam(cam: Cam, publish = true) { + loadCam(cam: Cam) { const self = this; const activities = self.graphToActivities(cam.graph); const molecules = self.graphToMolecules(cam.graph); From 5938b8025ec8a801e3457f23838af518a672be3a Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Wed, 11 Dec 2024 19:24:54 -0800 Subject: [PATCH 10/13] removed the dbxref lib and just made it inhouse (just took the same lib function) --- package-lock.json | 73 ++++------------- package.json | 3 +- src/components/gocam-viz/gocam-viz.tsx | 28 ++++--- .../@noctua.form/services/graph.service.ts | 21 +---- src/globals/constants.ts | 2 +- src/globals/dbxref.service.ts | 80 +++++++++++++++++++ 6 files changed, 118 insertions(+), 89 deletions(-) create mode 100644 src/globals/dbxref.service.ts diff --git a/package-lock.json b/package-lock.json index a09a1db..9235ad6 100644 --- a/package-lock.json +++ b/package-lock.json @@ -9,7 +9,6 @@ "version": "1.1.0-beta.0", "license": "BSD-3", "dependencies": { - "@geneontology/dbxrefs": "^1.0.16", "@stencil/core": "^4.1.0", "bbop-graph-noctua": "0.0.35", "cytoscape": "^3.16.1", @@ -17,6 +16,7 @@ "cytoscape-cose-bilkent": "^4.1.0", "cytoscape-dagre": "^2.4.0", "graphlib": "^2.1.8", + "js-yaml": "^4.1.0", "lodash": "^4.17.21", "moment": "^2.30.1", "uuid": "^8.3.2" @@ -24,18 +24,10 @@ "devDependencies": { "@rollup/plugin-image": "^3.0.3", "@stencil/sass": "^3.0.5", + "@types/js-yaml": "^4.0.9", "rollup-plugin-node-polyfills": "^0.2.1" } }, - "node_modules/@geneontology/dbxrefs": { - "version": "1.0.16", - "resolved": "https://registry.npmjs.org/@geneontology/dbxrefs/-/dbxrefs-1.0.16.tgz", - "integrity": "sha512-zKvbcfs+LU4ZnUo00A5ae0V+FVMIM4ftxcfKtJWmtnLKwWy1sOn2y36HGcz/rEmLwd2zBApKJ0ojmgBH416Q5Q==", - "dependencies": { - "axios": "^0.21.1", - "js-yaml": "^4.0.0" - } - }, "node_modules/@rollup/plugin-image": { "version": "3.0.3", "resolved": "https://registry.npmjs.org/@rollup/plugin-image/-/plugin-image-3.0.3.tgz", @@ -116,19 +108,17 @@ "integrity": "sha512-2JwWnHK9H+wUZNorf2Zr6ves96WHoWDJIftkcxPKsS7Djta6Zu519LarhRNljPXkpsZR2ZMwNCPeW7omW07BJw==", "dev": true }, + "node_modules/@types/js-yaml": { + "version": "4.0.9", + "resolved": "https://registry.npmjs.org/@types/js-yaml/-/js-yaml-4.0.9.tgz", + "integrity": "sha512-k4MGaQl5TGo/iipqb2UDG2UwjXziSWkh0uysQelTlJpX1qGlpUZYm8PnO4DxG1qBomtJUdYJ6qR6xdIah10JLg==", + "dev": true + }, "node_modules/argparse": { "version": "2.0.1", "resolved": "https://registry.npmjs.org/argparse/-/argparse-2.0.1.tgz", "integrity": "sha512-8+9WqebbFzpX9OR+Wa6O29asIogeRMzcGtAINdpMHHyAg10f05aSFVBbcEqGf/PXw1EjAZ+q2/bEBg3DvurK3Q==" }, - "node_modules/axios": { - "version": "0.21.1", - "resolved": "https://registry.npmjs.org/axios/-/axios-0.21.1.tgz", - "integrity": "sha512-dKQiRHxGD9PPRIUNIWvZhPTPpl1rf/OxTYKsqKUDjBwYylTvV7SjSHJb9ratfyzM6wCdLCOYLzs73qpg5c4iGA==", - "dependencies": { - "follow-redirects": "^1.10.0" - } - }, "node_modules/bbop-core": { "version": "0.0.5", "resolved": "https://registry.npmjs.org/bbop-core/-/bbop-core-0.0.5.tgz", @@ -287,25 +277,6 @@ "integrity": "sha512-SqmZANLWS0mnatqbSfRP5g8OXZC12Fgg1IwNtLsyHDzJizORW4khDfjPqJZsemPWBB2uqykUah5YpQ6epsqC/w==", "dev": true }, - "node_modules/follow-redirects": { - "version": "1.14.1", - "resolved": "https://registry.npmjs.org/follow-redirects/-/follow-redirects-1.14.1.tgz", - "integrity": "sha512-HWqDgT7ZEkqRzBvc2s64vSZ/hfOceEol3ac/7tKwzuvEyWx3/4UegXh5oBOIotkGsObyk3xznnSRVADBgWSQVg==", - "funding": [ - { - "type": "individual", - "url": "https://github.com/sponsors/RubenVerborgh" - } - ], - "engines": { - "node": ">=4.0" - }, - "peerDependenciesMeta": { - "debug": { - "optional": true - } - } - }, "node_modules/graphlib": { "version": "2.1.8", "resolved": "https://registry.npmjs.org/graphlib/-/graphlib-2.1.8.tgz", @@ -446,15 +417,6 @@ } }, "dependencies": { - "@geneontology/dbxrefs": { - "version": "1.0.16", - "resolved": "https://registry.npmjs.org/@geneontology/dbxrefs/-/dbxrefs-1.0.16.tgz", - "integrity": "sha512-zKvbcfs+LU4ZnUo00A5ae0V+FVMIM4ftxcfKtJWmtnLKwWy1sOn2y36HGcz/rEmLwd2zBApKJ0ojmgBH416Q5Q==", - "requires": { - "axios": "^0.21.1", - "js-yaml": "^4.0.0" - } - }, "@rollup/plugin-image": { "version": "3.0.3", "resolved": "https://registry.npmjs.org/@rollup/plugin-image/-/plugin-image-3.0.3.tgz", @@ -502,19 +464,17 @@ "integrity": "sha512-2JwWnHK9H+wUZNorf2Zr6ves96WHoWDJIftkcxPKsS7Djta6Zu519LarhRNljPXkpsZR2ZMwNCPeW7omW07BJw==", "dev": true }, + "@types/js-yaml": { + "version": "4.0.9", + "resolved": "https://registry.npmjs.org/@types/js-yaml/-/js-yaml-4.0.9.tgz", + "integrity": "sha512-k4MGaQl5TGo/iipqb2UDG2UwjXziSWkh0uysQelTlJpX1qGlpUZYm8PnO4DxG1qBomtJUdYJ6qR6xdIah10JLg==", + "dev": true + }, "argparse": { "version": "2.0.1", "resolved": "https://registry.npmjs.org/argparse/-/argparse-2.0.1.tgz", "integrity": "sha512-8+9WqebbFzpX9OR+Wa6O29asIogeRMzcGtAINdpMHHyAg10f05aSFVBbcEqGf/PXw1EjAZ+q2/bEBg3DvurK3Q==" }, - "axios": { - "version": "0.21.1", - "resolved": "https://registry.npmjs.org/axios/-/axios-0.21.1.tgz", - "integrity": "sha512-dKQiRHxGD9PPRIUNIWvZhPTPpl1rf/OxTYKsqKUDjBwYylTvV7SjSHJb9ratfyzM6wCdLCOYLzs73qpg5c4iGA==", - "requires": { - "follow-redirects": "^1.10.0" - } - }, "bbop-core": { "version": "0.0.5", "resolved": "https://registry.npmjs.org/bbop-core/-/bbop-core-0.0.5.tgz", @@ -645,11 +605,6 @@ "integrity": "sha512-SqmZANLWS0mnatqbSfRP5g8OXZC12Fgg1IwNtLsyHDzJizORW4khDfjPqJZsemPWBB2uqykUah5YpQ6epsqC/w==", "dev": true }, - "follow-redirects": { - "version": "1.14.1", - "resolved": "https://registry.npmjs.org/follow-redirects/-/follow-redirects-1.14.1.tgz", - "integrity": "sha512-HWqDgT7ZEkqRzBvc2s64vSZ/hfOceEol3ac/7tKwzuvEyWx3/4UegXh5oBOIotkGsObyk3xznnSRVADBgWSQVg==" - }, "graphlib": { "version": "2.1.8", "resolved": "https://registry.npmjs.org/graphlib/-/graphlib-2.1.8.tgz", diff --git a/package.json b/package.json index 54ba0bc..734e56d 100644 --- a/package.json +++ b/package.json @@ -22,7 +22,6 @@ "generate": "stencil generate" }, "dependencies": { - "@geneontology/dbxrefs": "^1.0.16", "@stencil/core": "^4.1.0", "bbop-graph-noctua": "0.0.35", "cytoscape": "^3.16.1", @@ -30,6 +29,7 @@ "cytoscape-cose-bilkent": "^4.1.0", "cytoscape-dagre": "^2.4.0", "graphlib": "^2.1.8", + "js-yaml": "^4.1.0", "lodash": "^4.17.21", "moment": "^2.30.1", "uuid": "^8.3.2" @@ -37,6 +37,7 @@ "devDependencies": { "@rollup/plugin-image": "^3.0.3", "@stencil/sass": "^3.0.5", + "@types/js-yaml": "^4.0.9", "rollup-plugin-node-polyfills": "^0.2.1" }, "repository": { diff --git a/src/components/gocam-viz/gocam-viz.tsx b/src/components/gocam-viz/gocam-viz.tsx index b88ff76..c87c496 100644 --- a/src/components/gocam-viz/gocam-viz.tsx +++ b/src/components/gocam-viz/gocam-viz.tsx @@ -2,7 +2,6 @@ import { Component, Host, Prop, Element, Event, EventEmitter, Watch, h } from '@ import { Listen, Method, State } from '@stencil/core'; import cytoscape from 'cytoscape'; import dagre from 'cytoscape-dagre'; -import * as dbxrefs from "@geneontology/dbxrefs"; import { Activity, ActivityType, Cam, ActivityNodeType, @@ -11,6 +10,7 @@ import { Triple } from '../../globals/@noctua.form'; import { glyph } from '../../globals/relations'; +import { DBXrefService } from '../../globals/dbxref.service'; @@ -71,8 +71,10 @@ export class GoCamViz { */ @State() error: boolean = false; + dbxrefService = new DBXrefService(); configService = new NoctuaFormConfigService(); - graphService = new NoctuaGraphService(this.configService) + + graphService = new NoctuaGraphService(this.configService, this.dbxrefService) // variables for bbop graph currentGraph = undefined; @@ -259,13 +261,6 @@ export class GoCamViz { } } - - relations_enabled_by = ['http://purl.obolibrary.org/obo/RO_0002333', 'RO_0002333', 'RO:0002333']; - relations_collapsible = ["RO:0002333", "BFO:0000066", "RO:0002233", "RO:0002488", "RO:0002234"]; // 2233 : has input ; 2234 : has output - // relations_collapsible = ["RO:0002333", "BFO:0000066", "RO:0002233", "RO:0002488", "RO:0002234"]; // 2233 : has input ; 2234 : has output - relations_nestable = {}; - - initCytoscape() { cytoscape.use(dagre); } @@ -274,8 +269,19 @@ export class GoCamViz { * Init the GO dbxrefs.yaml, in order to build URL meta */ async initDBXrefs() { - await dbxrefs.init(); - this.dbXrefsReady = true; + try { + await this.dbxrefService.init(); + while (!this.dbxrefService.isReady()) { + await new Promise(resolve => setTimeout(resolve, 100)); + } + if (this.dbxrefService.hasError()) { + throw new Error('Failed to initialize dbxrefs'); + } + this.dbXrefsReady = true; + } catch (error) { + console.error('Failed to initialize dbxrefs:', error); + this.dbXrefsReady = false; + } } /** diff --git a/src/globals/@noctua.form/services/graph.service.ts b/src/globals/@noctua.form/services/graph.service.ts index b8a5201..eff10cd 100644 --- a/src/globals/@noctua.form/services/graph.service.ts +++ b/src/globals/@noctua.form/services/graph.service.ts @@ -13,21 +13,17 @@ import { Triple } from './../models/activity/triple'; import { TermsSummary } from './../models/activity/summary'; import moment from 'moment'; import { graph as bbopGraph } from 'bbop-graph-noctua'; -import * as dbxrefs from "@geneontology/dbxrefs"; +import { DBXrefService } from '../../dbxref.service'; export class NoctuaGraphService { - curieUtil: any; - constructor( - public noctuaFormConfigService: NoctuaFormConfigService) { + public noctuaFormConfigService: NoctuaFormConfigService, + private dbXrefService: DBXrefService) { } - getTermURL(id: string) { - const self = this; - if (!id) { return "" } @@ -45,9 +41,8 @@ export class NoctuaGraphService { } else { const dbId = id.split(/:(.+)/, 2); if (dbId.length > 1) { - return dbxrefs.getURL(dbId[0], undefined, dbId[1]); + return this.dbXrefService.getURL(dbId[0], undefined, dbId[1]); } - } } @@ -65,7 +60,6 @@ export class NoctuaGraphService { } - getMetadata(responseData) { const self = this; const cam = new Cam() @@ -98,10 +92,8 @@ export class NoctuaGraphService { }) return cam; - } - loadCam(cam: Cam) { const self = this; const activities = self.graphToActivities(cam.graph); @@ -118,8 +110,6 @@ export class NoctuaGraphService { cam.updateActivityDisplayNumber(); } - - getNodeInfo(node) { const result: any = {}; @@ -134,7 +124,6 @@ export class NoctuaGraphService { return result; } - getNodeRootInfo(node): Entity[] { const result = node.root_types().map((srcType) => { const type = srcType.type() === 'complement' ? srcType.complement_class_expression() : srcType; @@ -222,7 +211,6 @@ export class NoctuaGraphService { return new ActivityNode(result); } - edgeComments(edge): string[] { const commentAnnotations = edge.get_annotations_by_key('comment'); @@ -230,7 +218,6 @@ export class NoctuaGraphService { return commentAnnotations.map(c => { return c.value(); }) - } edgeToEvidence(graph, edge): Evidence[] { diff --git a/src/globals/constants.ts b/src/globals/constants.ts index 8bb7cf3..ee2e44e 100644 --- a/src/globals/constants.ts +++ b/src/globals/constants.ts @@ -1 +1 @@ -export const curieUrl = "https://raw.githubusercontent.com/prefixcommons/biocontext/master/registry/go_context.jsonld"; +export const DB_XREFS_URL = 'https://current.geneontology.org/metadata/db-xrefs.json'; \ No newline at end of file diff --git a/src/globals/dbxref.service.ts b/src/globals/dbxref.service.ts new file mode 100644 index 0000000..2303704 --- /dev/null +++ b/src/globals/dbxref.service.ts @@ -0,0 +1,80 @@ +import { load as yamlLoad } from 'js-yaml'; +import { DB_XREFS_URL } from './constants'; + +interface EntityType { + type_name: string; + url_syntax: string; +} + +interface DBXref { + database: string; + synonyms?: string[]; + entity_types: EntityType[]; +} + +export class DBXrefService { + private url = DB_XREFS_URL; + private dbxrefs: DBXref[] | null = null; + private isInitialized = false; + private hasInitError = false; + + constructor() { + } + + public getURL(database: string, entityType: string | undefined, id: string): string | undefined { + if (!this.dbxrefs) { + throw new Error('Database not initialized. Call init() first'); + } + + let db = this.dbxrefs.filter(elt => + elt.database.toLowerCase() === database.toLowerCase() || + (elt.synonyms && elt.synonyms.includes(database)) + ); + + if (!db || db.length === 0) { + console.warn("@geneontology/dbxrefs: database ", database, " not found for requested id ", id); + return undefined; + } + + let entity; + if (entityType) { + entity = db[0].entity_types.filter(elt => elt.type_name.toLowerCase() === entityType.toLowerCase()); + } else { + entity = [db[0].entity_types[0]]; + } + + if (!entity || entity.length === 0) { + console.warn("@geneontology/dbxrefs: entity ", entityType, " not found in database ", database); + return undefined; + } + + entity = entity[0]; + return entity.url_syntax.replace("[example_id]", id); + } + + public async init(): Promise { + try { + const response = await fetch(this.url); + if (!response.ok) throw new Error(`HTTP error! status: ${response.status}`); + const text = await response.text(); + this.dbxrefs = yamlLoad(text) as DBXref[]; + this.isInitialized = true; + } catch (error) { + this.hasInitError = true; + this.isInitialized = true; + throw error; + } + } + + public isReady(): boolean { + return this.isInitialized; + } + + public hasError(): boolean { + return this.hasInitError; + } + + public getDBXrefs(): DBXref[] | null { + return this.dbxrefs; + } +} \ No newline at end of file From 25eafc88fda64a9ad274246a2a21f09aea470695 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Thu, 12 Dec 2024 10:36:44 -0800 Subject: [PATCH 11/13] fixed the styling and 'part' --- src/components/gocam-legend/gocam-legend.tsx | 6 +++--- src/components/gocam-viz/gocam-viz.scss | 11 +---------- 2 files changed, 4 insertions(+), 13 deletions(-) diff --git a/src/components/gocam-legend/gocam-legend.tsx b/src/components/gocam-legend/gocam-legend.tsx index 810dfd8..091fbcd 100644 --- a/src/components/gocam-legend/gocam-legend.tsx +++ b/src/components/gocam-legend/gocam-legend.tsx @@ -43,10 +43,10 @@ export class GocamLegend { -
Relation Types
-
+
Relation Types
+
{Object.entries(LEGEND_COLUMNS).map(([columnName, relations]) => ( -
+
{Object.entries(relations).map(([relationId, label]) => { const config = RELATION_MAP[relationId]; return ( diff --git a/src/components/gocam-viz/gocam-viz.scss b/src/components/gocam-viz/gocam-viz.scss index da235d7..d87c8c0 100644 --- a/src/components/gocam-viz/gocam-viz.scss +++ b/src/components/gocam-viz/gocam-viz.scss @@ -27,6 +27,7 @@ * * @prop --legend-border-color: Border color of legend container * @prop --legend-border-width: Border width of legend container + * @prop --legend-margin: Margin of legend container * @prop --legend-padding: Padding of legend container * * @prop --legend-header-background: Background of legend header @@ -116,16 +117,6 @@ @include standard-var-declarations(node, $border-color: var(--border-color), $padding: 0 1em 0 0); --function-nodes-padding: 0; - - display: flex; - align-items: stretch; - flex-direction: column; -} - -.gocam-container { - height: 100%; - display: flex; - flex-direction: column; } .gocam-graph-and-activities-container { From 690c102ae80cb3622af982e5c18f719536fc5e69 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Thu, 12 Dec 2024 11:04:28 -0800 Subject: [PATCH 12/13] fixed the traingle, now pointy and the provides input for glyph --- src/components/gocam-legend/gocam-legend.tsx | 17 +++++++++++------ src/components/gocam-viz/readme.md | 1 + 2 files changed, 12 insertions(+), 6 deletions(-) diff --git a/src/components/gocam-legend/gocam-legend.tsx b/src/components/gocam-legend/gocam-legend.tsx index 091fbcd..389d9b2 100644 --- a/src/components/gocam-legend/gocam-legend.tsx +++ b/src/components/gocam-legend/gocam-legend.tsx @@ -28,14 +28,19 @@ export class GocamLegend { markerWidth="12" markerHeight="4" orient="auto"> - - + + : - - {config.glyph === 'triangle' && } - {config.glyph === 'tee' && } + + {config.glyph === 'triangle' && } + {config.glyph === 'tee' && } {config.glyph === 'circle' && } {config.glyph === 'square' && } diff --git a/src/components/gocam-viz/readme.md b/src/components/gocam-viz/readme.md index 7fcca95..1d761e2 100644 --- a/src/components/gocam-viz/readme.md +++ b/src/components/gocam-viz/readme.md @@ -123,6 +123,7 @@ Type: `Promise` | `--legend-header-border-width` | Border width of legend header | | `--legend-header-color` | Text color of legend header | | `--legend-header-padding` | Padding of legend header | +| `--legend-margin` | Margin of legend container | | `--legend-padding` | Padding of legend container | | `--node-background` | Background of related node info in processes and activities panel | | `--node-border-color` | Border color of related node info in processes and activities panel | From d9f277b9ce469cf2d6caff17ca0b913f301e8a70 Mon Sep 17 00:00:00 2001 From: tmushayahama Date: Thu, 12 Dec 2024 12:10:08 -0800 Subject: [PATCH 13/13] reduced the code and used one marker def --- src/components/gocam-legend/gocam-legend.tsx | 44 +++++++++----------- 1 file changed, 19 insertions(+), 25 deletions(-) diff --git a/src/components/gocam-legend/gocam-legend.tsx b/src/components/gocam-legend/gocam-legend.tsx index 389d9b2..edf15a5 100644 --- a/src/components/gocam-legend/gocam-legend.tsx +++ b/src/components/gocam-legend/gocam-legend.tsx @@ -1,4 +1,4 @@ -import { Component, Host, h } from '@stencil/core'; +import { Component, Fragment, Host, h } from '@stencil/core'; import { RELATION_MAP, STYLES } from '../../globals/relations'; import { LEGEND_COLUMNS } from '../../globals/legend'; @@ -20,30 +20,24 @@ export class GocamLegend { {Object.entries(RELATION_MAP).map(([id, config]) => ( - config.glyph === 'circle-triangle' ? - - - - - : - - {config.glyph === 'triangle' && } - {config.glyph === 'tee' && } - {config.glyph === 'circle' && } - {config.glyph === 'square' && } - + + {config.glyph === 'circle-triangle' && ( + + + + + )} + {config.glyph === 'triangle' && } + {config.glyph === 'tee' && } + {config.glyph === 'circle' && } + {config.glyph === 'square' && } + ))}