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metadata-NotreDame-FRED.txt
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metadata-NotreDame-FRED.txt
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team_name: NotreDame-FRED
model_name: NotreDame-FRED
model_abbr: NotreDame-FRED
model_contributors: 'guido espana <[email protected]>, rachel oidtman, sean cavany, alan
costello, anneliese wieler, anita lerch, carly barbera, marya poterek, quan
tran, sean moore, alex perkins <[email protected]> '
website_url: https://github.com/confunguido/covid19_ND_forecasting
license: cc-by-4.0
team_model_designation: secondary
ensemble_of_hub_models: false
methods: FRED is an agent-based model developed for influenza with parameters modified
to represent the natural history of COVID-19
team_funding: GE and TAP were supported by a RAPID grant from the National Science
Foundation (DEB 2027718).
data_inputs: NYTimes Daily reported deaths count
methods_long: "We used an existing agent-based model, FRED (Framework for Reconstructing\
\ Epidemic Dynamics) which was developed by the university of Pittsburgh in response\
\ to the 2009 influenza pandemic (Grefenstette et al. 2013). We modified the model\
\ parameters to represent the natural history of COVID-19 and calibrated a set of\
\ parameters to reproduce current trends of deaths due to COVID-19 in the US. FRED\
\ simulates the spread of the virus in a population by recreating interactions among\
\ people on a daily basis. To accurately represent the population of each of the\
\ states simulated, we used a synthetic population of the US that represents demographic\
\ and geographic characteristics of the population in 2010 (Wheaton 2012). Each\
\ human is modeled as an agent that visits a set of places defined by their activity\
\ space. This activity space contains places such as households, schools, workplaces,\
\ or neighborhood locations. Transmission of SARS-CoV-2 can occur when an infected\
\ person visits the same location as a susceptible person on the same day. Numbers\
\ of contacts per person are specific to each place type. For instance, school contacts\
\ do not depend on the size of the school but the age of the agent. Infected agents\
\ have a probability to stay at home if they develop symptoms. Those who do not\
\ stay at home continue their daily activities. Public health interventions are\
\ included in the model to represent the changes in agents\u2019 behavior in response\
\ to an epidemic. In this study, we limited the interventions to school closure\
\ and shelter in place. Schools are closed on a specific date to represent state-level\
\ guidelines (IHME COVID-19 health service utilization forecasting Team and Murray\
\ 2020). In the case that schools are closed, students limit their activity space\
\ to household or neighborhood locations. Shelter-in-place interventions reduce\
\ each agent\u2019s activity space to their household at a compliance level from\
\ 0-100%, which was estimated as part of the model calibration. Agents who do not\
\ comply with the shelter-in-place orders continue with their daily routines. We\
\ used state-level orders to determine the date at which people are advised to shelter\
\ in place (IHME COVID-19 health service utilization forecasting Team and Murray\
\ 2020). See the methods file in our repo for more detailed methods and model limitations.\n\
Updates 2020-05-11 - We updated our likelihood used in our calibration, switching\
\ from a Poisson to a negative binomial distribution in order to allow for greater\
\ over-dispersion in the distribution of deaths. - We changed the way that we calculate\
\ the proportion of the population that is sheltering in place. We no longer use\
\ the dates at which government advisories were issued. Instead, we now exclusively\
\ use the google mobility data (https://www.google.com/covid19/mobility/) on journeys\
\ made to residential locations. We calibrate the maximum compliance to shelter\
\ in place, and use a generalized additive model fitted to the google data to forecast\
\ movement in the coming 5 weeks. For more details on this approach, see the methods\
\ file in our repo."