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New changes for KAHP/SK2 channel
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| TITLE Mod file for component: Component(id=CaClamp type=caClamp) | ||
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| COMMENT | ||
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| This NEURON file has been generated by org.neuroml.export (see https://github.com/NeuroML/org.neuroml.export) | ||
| org.neuroml.export v1.4.3 | ||
| org.neuroml.model v1.4.3 | ||
| jLEMS v0.9.8.1 | ||
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| ENDCOMMENT | ||
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| NEURON { | ||
| SUFFIX CaClamp | ||
| USEION ca READ cai, cao, ica WRITE cai VALENCE 2 | ||
| RANGE cai | ||
| RANGE cao | ||
| GLOBAL initialConcentration | ||
| GLOBAL initialExtConcentration | ||
| RANGE conc0 : parameter | ||
| RANGE conc1 : parameter | ||
| RANGE delay : parameter | ||
| RANGE duration : parameter | ||
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| } | ||
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| UNITS { | ||
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| (nA) = (nanoamp) | ||
| (uA) = (microamp) | ||
| (mA) = (milliamp) | ||
| (A) = (amp) | ||
| (mV) = (millivolt) | ||
| (mS) = (millisiemens) | ||
| (uS) = (microsiemens) | ||
| (molar) = (1/liter) | ||
| (kHz) = (kilohertz) | ||
| (mM) = (millimolar) | ||
| (um) = (micrometer) | ||
| (umol) = (micromole) | ||
| (S) = (siemens) | ||
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| } | ||
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| PARAMETER { | ||
| surfaceArea (um2) | ||
| iCa (nA) | ||
| initialConcentration (mM) | ||
| initialExtConcentration (mM) | ||
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| conc0 = 5.0E-5 (mM) | ||
| conc1 = 0.005 (mM) | ||
| delay = 200 (ms) | ||
| duration = 200 (ms) | ||
| } | ||
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| ASSIGNED { | ||
| cai (mM) | ||
| cao (mM) | ||
| ica (mA/cm2) | ||
| diam (um) | ||
| area (um2) | ||
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| } | ||
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| STATE { | ||
| concentration (mM) | ||
| extConcentration (mM) | ||
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| } | ||
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| INITIAL { | ||
| initialConcentration = cai | ||
| initialExtConcentration = cao | ||
| rates() | ||
| rates() ? To ensure correct initialisation. | ||
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| concentration = initialConcentration | ||
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| extConcentration = initialExtConcentration | ||
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| } | ||
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| BREAKPOINT { | ||
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| rates() | ||
| if (t <= delay) { | ||
| concentration = conc0 ? standard OnCondition | ||
| } | ||
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| if (t >= delay && t <= duration + delay) { | ||
| concentration = conc1 ? standard OnCondition | ||
| } | ||
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| if (t >= duration + delay) { | ||
| concentration = conc0 ? standard OnCondition | ||
| } | ||
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| cai = concentration | ||
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| } | ||
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| PROCEDURE rates() { | ||
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| surfaceArea = area : surfaceArea has units (um2), area (built in to NEURON) is in um^2... | ||
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| iCa = -1 * (0.01) * ica * surfaceArea : iCa has units (nA) ; ica (built in to NEURON) has units (mA/cm2)... | ||
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| } | ||
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